Pathophysiology of severe burns: Fundamentals for early and anticipatory management by the general practitioner
DOI:
https://doi.org/10.52611/confluencia.2026.1798Keywords:
Burns, Metabolic stress, Endothelium, Glycocalyx, Skin physiological phenomenaAbstract
References
1. Abraham JP, Plourde BD, Vallez LJ, Nelson-Cheeseman BB, Stark JR, Sparrow EM et al. Skin burns. En: D. Shrivastava, editor. Theory and applications of heat transfer in humans [Internet]. Hoboken: John Wiley & Sons; 2018 [citado el 23 de mayo 2026]. p. 723-39. Disponible en: https://doi.org/10.1002/9781119127420.ch33
2. Organización Mundial de la Salud. Quemaduras [Internet]. Ginebra: OMS; 2023 [citado el 23 de mayo 2026]. Disponible en: https://www.who.int/es/news-room/fact-sheets/detail/burns
3. ISBI Practice Guidelines Committee; Steering Subcommittee; Advisory Subcommittee. ISBI Practice Guidelines for Burn Care. Burns [Internet]. 2016 [citado el 23 de mayo 2026];42(5):953-1021. Disponible en: https://doi.org/10.1016/j.burns.2016.05.013
4. Jeschke MG, van Baar ME, Choudhry MA, Chung KK, Gibran NS, Logsetty S. Burn injury. Nat Rev Dis Primers [Internet]. 2020 [citado el 23 de mayo 2026];6(1):11. Disponible en: https://doi.org/10.1038/s41572-020-0145-5
5. Ministerio de Salud de Chile. Guía clínica AUGE. Gran quemado [Internet]. Santiago: MINSAL; 2016 [citado el 23 de mayo 2026]. Disponible en: https://diprece.minsal.cl/wrdprss_minsal/wp-content/uploads/2016/04/GPC-GRAN-QUEMADO-FINAL-18-MARZO-2016_DIAGRAMADA.pdf
6. Barrett LW, Fear VS, Waithman JC, Wood FM, Fear MW. Understanding acute burn injury as a chronic disease. Burns Trauma [Internet]. 2019 [citado el 23 de mayo 2026];7:23. Disponible en: https://doi.org/10.1186/s41038-019-0163-2
7. Jeschke MG. Postburn Hypermetabolism: Past, Present, and Future. J Burn Care Res [Internet]. 2016 [citado el 23 de mayo 2026];37(2):86-96. Disponible en: https://doi.org/10.1097/BCR.0000000000000265
8. Hoss E, Dugdale DC. Quemaduras [Internet]. Bethesda: MedlinePlus; 2022 [citado el 23 de mayo 2026]. Disponible en: https://medlineplus.gov/spanish/ency/article/000030.htm
9. Pruthi S. Burns [Internet]. Rochester: Mayo Clinic; 2022 [citado el 23 de mayo 2026]. Disponible en: https://www.mayoclinic.org/diseases-conditions/burns/symptoms-causes/syc-20370539
10. Orgill DP, Jeschke MG, Collins KA. Assessment and classification of burn injury [Internet]. Waltham: UpToDate; 2023 [citado el 23 de mayo 2026]. Disponible en: https://www.uptodate.com/contents/assessment-and-classification-of-burn-injury
11. Schaefer TJ, Szymanski KD. Burn Evaluation and Management [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 [citado el 23 de mayo 2026]. Disponible en: https://www.ncbi.nlm.nih.gov/books/NBK430741/
12. Kaddoura I, Abu-Sittah G, Ibrahim A, Karamanoukian R, Papazian N. Burn injury: review of pathophysiology and therapeutic modalities in major burns. Ann Burns Fire Disasters [Internet]. 2017 [citado el 23 de mayo 2026];30(2):95-102. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627549/
13. Bitter CC, Storkan M, Overmiller A, Respicio JA, McGowan T, Park A, et al. Wilderness Medical Society Clinical Practice Guideline on Care of Burns in the Wilderness. Wilderness Environ Med [Internet]. 2025 [citado el 28 de julio 2026];36(4):549-58. Disponible en: https://doi.org/10.1177/10806032251345768
14. Hemmati S. Burn shock: Pathogenesis, complications, and clinical findings [Internet]. Calgary: Calgary Guide; 2022 [citado el 23 de mayo 2026]. Disponible en: https://calgaryguide.ucalgary.ca/burn-shock-pathogenesis-complications-and-clinical-findings/
15. Dobson GP, Morris JL, Letson HL. Pathophysiology of Severe Burn Injuries: New Therapeutic Opportunities From a Systems Perspective. J Burn Care Res [Internet]. 2024 [citado el 28 de julio 2026];45(4):1041-50. Disponible en: https://doi.org/10.1093/jbcr/irae049
16. Eslinger A, Hansen E. Superficial Thickness Burns: Pathogenesis and Clinical Findings [Internet]. Calgary: Calgary Guide; 2023 [citado el 23 de mayo 2026]. Disponible en: https://calgaryguide.ucalgary.ca/superficial-thickness-burns-pathogenesis-and-clinical-findings/
17. Eslinger A, Rice T. Full thickness burns: Pathogenesis and clinical findings [Internet]. Calgary: Calgary Guide; 2023 [citado el 23 de mayo 2026]. Disponible en: https://calgaryguide.ucalgary.ca/burns-full-thickness-pathogenesis-and-clinical-findings-2023/
18. Clark A, Neyra JA, Madni T, Imran J, Phelan H, Arnoldo B, et al. Acute kidney injury after burn. Burns [Internet]. 2017 [citado el 23 de mayo 2026];43(5):898-908. Disponible en: https://doi.org/10.1016/j.burns.2017.01.023
19. VanHoy TB, Metheny H, Patel BC. Chemical Burns [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 [citado el 23 de mayo 2026]. Disponible en: https://www.ncbi.nlm.nih.gov/books/NBK499888/
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