Hospitalizaciones por enfermedad celíaca en Chile durante el periodo 2020-2023
DOI:
https://doi.org/10.52611/confluencia.2025.1344Keywords:
Epidemiología, Enfermedad celíaca, Hospitalizaciones, GastroenterologíaAbstract
ABSTRACT
Introduction: Celiac disease is an autoimmune disorder characterized by an abnormal immune response to gluten, with potentially complications, highlighting the importance of epidemiological monitoring. Objective: To describe the hospital discharge rate for celiac disease during the period 2020-2023 in Chile. Materials and Methods: Observational, descriptive, and retrospective study. Using data from the Department of Health Statistics and Information and the National Institute of Statistics of Chile, an analysis of the hospital discharge rate for celiac disease was conducted for the period 2020-2023, categorized by sex, age group, and clinical presentation. Results: A total of 336 hospital discharges were recorded, determining a period discharge rate of 0.48 discharges per 100,000 inhabitants. The highest rate was observed in 2022, with a predominance of female patients. The highest discharge rate was recorded in patients aged 5 to 9 years. Additionally, 2022 was identified as the year with the longest hospital stay, averaging 9 days. Discussion: The hospital discharge rate for celiac disease in Chile between 2020 and 2023 reflects trends that may have been influenced by external factors, such as the COVID-19 pandemic. The higher rates observed in children and older adults indicate greater susceptibility to complications in these age groups. Conclusion: The influence of epidemiological, clinical, and contextual factors on the observed trends is evident, reinforcing the need for a differentiated approach to diagnosis.
Keywords: Celiac Disease; Epidemiology; Hospitalization; Gastroenterology.
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Lebwohl B, Rubio-Tapia A. Epidemiology, presentation, and diagnosis of celiac disease. Gastroenterology [Internet]. 2020 [citado el 18 de julio 2020];160(1):63-75. Disponible en: https://doi.org/10.1053/j.gastro.2020.06.098
Iversen R, Sollid LM. The immunobiology and pathogenesis of celiac disease. Annu Rev Pathol [Internet]. 2022 [citado el 19 de marzo 2025];18:47-70. Disponible en: http://dx.doi.org/10.1146/annurev-pathmechdis-031521-032634
Von Mühlenbrock-Pinto C, Madrid-Silva AM. Celiac disease in Chilean adults. Rev Gastroenterol Méx (Engl Ed) [Internet]. 2023 [citado el 19 de marzo 2025];88(1):28-35. Disponible en: https://doi.org/10.1016/j.rgmxen.2022.03.007
Catassi C, Verdu EF, Bai JC, Lionetti E. Coeliac disease. Lancet [Internet]. 2022 [citado el 19 de marzo 2025];399(10344):2413-26. Disponible en: https://doi.org/10.1016/s0140-6736(22)00794-2
Consejería de Salud y Consumo de la Junta de Andalucía. Guía para el diagnóstico y seguimiento de la enfermedad celíaca en Andalucía [Internet]. Sevilla: Servicio Andaluz de Salud; 2023 [citado el 19 de marzo 2025]. Disponible en: https://www.sspa.juntadeandalucia.es/servicioandaluzdesalud/publicaciones/guia-para-el-diagnostico-y-seguimiento-de-la-enfermedad-celiaca-en-andalucia
Dahiya DS, Al-Haddad M, Perisetti A, Singh A, Goyal H, Cheng CI, et al. Celiac disease hospitalizations: an emerging challenge in the United States. Ann Gastroenterol [Internet]. 2022 [citado el 19 de marzo 2025];35(4):383-92 Disponible en: https://doi.org/10.20524/aog.2022.0724
Ministerio de Salud, Chile. Egresos hospitalarios por diagnóstico principal según causa y sexo [Internet]. Santiago: DEIS; 2024 [citado el 3 de junio 2025]. Disponible en: https://deis.minsal.cl/egresos-hospitalarios/
Instituto Nacional de Estadísticas. Proyecciones y estimaciones de población. Total país 1992-2050 [Internet]. Santiago: INE; 2024 [citado el 3 de junio 2025]. Disponible en: https://www.ine.gob.cl/estadisticas/sociales/demografia-y-vitales/proyecciones-de-poblacion
Lazzerini M, Barbi E, Apicella A, Marchetti F, Cardinale F, Trobia G. Delayed access or provision of care in Italy resulting from fear of COVID-19. Lancet Child Adolesc Health [Internet]. 2020 [citado el 19 de marzo 2025];4(5):e10-1. Disponible en: https://doi.org/10.1016/S2352-4642(20)30108-5
Czeisler ME, Marynak K, Clarke KE, Salah Z, Shakya I, Thierry J, et al. Delay or avoidance of medical care because of COVID-19. Morb Mortal Wkly Rep [Internet]. 2020 [citado el 19 de marzo 2025];69(36):1250-7. Disponible en: http://dx.doi.org/10.15585/mmwr.mm6936a4
Hadi YB, Sohail AH, Lakhani DA, Naqvi SF, Kupec JT, Pervez A. Outcomes of SARS-CoV-2 infection in patients with celiac disease: a multicenter research network study. Ann Gastroenterol [Internet]. 2022 [citado el 19 de marzo 2025];35(2):164-8. Disponible en: https://doi.org/10.20524/aog.2022.0691
Amirian P, Zarpoosh M, Moradi S, Jalili C. Celiac disease and COVID-19 in adults: A systematic review. PLoS One [Internet]. 2023 [citado el 19 de marzo 2025];18(5):e0285880. Disponible en: https://doi.org/10.1371/journal.pone.0285880
Cohen BS, Lebwohl B. COVID-19 and celiac disease: a review. Therap Adv Gastroenterol [Internet]. 2023 [citado el 19 de marzo 2025];16:17562848231153944. Disponible en: https://doi.org/10.1177/17562848231170944
Kivelä L, Caminero A, Leffler DA, Pinto-Sanchez MI, Tye-Din JA, Lindfors K. Current and emerging therapies for coeliac disease. Nat Rev Gastroenterol Hepatol [Internet]. 2021 [citado el 8 de junio 2025];18(3):181-95. Disponible en: https://doi.org/10.1038/s41575-020-00378-1
Valitutti F, Cucchiara S, Fasano A. Celiac disease and the microbiome. Nutrients [Internet]. 2019 [citado el 19 de marzo 2025];11(10):2403. Disponible en: https://doi.org/10.3390/nu11102403
Lionetti E, Catassi C. The role of environmental factors in the development of celiac disease: what is new? J Pediatr Gastroenterol Nutr [Internet]. 2015 [citado el 19 de marzo 2025];3(4):282-93. Disponible en: https://doi.org/10.3390/diseases3040282
Lopes EW, Lebwohl B, Burke KE, Ivey KL, Ananthakrishnan AN, Lochhead P, et al. Dietary gluten intake is not associated with risk of inflammatory bowel disease in US adults without celiac disease. Clin Gastroenterol Hepatol [Internet]. 2022 [citado el 19 de marzo 2025];20(2):303-13.E6. Disponible en: https://doi.org/10.1016/j.cgh.2021.03.029
Ching CK, Lebwohl B. Celiac disease in the elderly. Curr Treat Options Gastroenterol [Internet]. 2022 [citado el 8 de abril 2025];20(3):238-49. Disponible en: https://doi.org/10.1007/s11938-022-00397-8
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