Amoebic liver abscess: a case report from Santiago, Chile.

Authors

  • Simona Oviedo Bravo Estudiante de Medicina, Facultad de Medicina - Universidad de los Andes , Chile
  • Nicolás Muñoz Gardilcic Estudiante de Medicina, Facultad de Medicina - Universidad de los Andes , Chile

DOI:

https://doi.org/10.52611/confluencia.num1.2023.923

Keywords:

Liver Abscess, Liver Abscess, Amebic, Amebiasis, Entamoeba histolytica

Abstract

Liver abscess is a focal suppurative process, mainly of pyogenic and/or amoebic aetiology, the latter caused by the protozoan Entamoeba histolytica. Infection by this parasite in Chile has a prevalence of 3 to 18%. The infection is generally asymptomatic; however, 10% of cases present with symptoms, frequently diarrhoea and abdominal pain. Among the extraintestinal manifestations, amoebic liver abscess stands out. The diagnosis is made through serial parasitological and serological techniques for intra- or extraintestinal manifestations, respectively. Treatment of amoebic liver abscess consists of amoebicides and early drainage. Methodology: We present the case of a young, healthy male patient with epidemiological risk factors for infection due to living in areas of high Entamoeba endemicity and exposure to non-potable water. A literature review was conducted on liver abscess and its correct clinical therapeutic approach, with an emphasis on amoebic aetiology, in relation to the case. Results: The patient presented with a clinical picture characterised by fever, abdominal pain in the hypogastrium radiating to the epigastrium and right chest and shoulder, as well as changes in bowel movements. Imaging revealed a large, single liver abscess suggestive of amoebic origin. It was treated empirically with a dual antibiotic regimen while awaiting the results of serology for Entamoeba histolytica, which were positive. Discussion: The patient responds well to treatment, with no complications. Conclusion: The importance of diagnostic and therapeutic precision is emphasised, including luminal eradication of the parasite, a treatment that is not yet available in Chile, given the current migratory context in the country.

Downloads

Download data is not yet available.

References

Cosme Á, Cobián C. Abscesos hepáticos. Rev Esp Enferm Dig [Internet]. 2014 [citado el 13 de mayo de 2023];106(5):359. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid= S1130-01082014000500011&lng=es

Altemeier WA, Culbertson WR, Fullen WD, Shook CD. Intra-abdominal abscesses. Am J Surg [Internet]. 1973 [citado el 15 de mayo de 2023];125(1):70-9. Disponible en: https://doi.org/10.1016/0002-9610(73)90010-x

Fleta J, Bueno O, Bueno M. Amebiasis intestinal y absceso hepático amebiano. Med Integr [Internet]. 2000 [citado el 15 de mayo de 2023];36(3):96-101. Disponible en: https://www.elsevier.es/es-revista- medicina-integral-63-articulo-amebiasis-intestinal- absceso-hepatico-amebiano-15325

Torre A. Enfermedades hepáticas infecciosas. Abscesos hepáticos. GH Cont [Internet]. 2006 [citado el 15 de mayo de 2023];5(5):201-7. Disponible en: https://www.elsevier.es/es-revista-offarm-4-pdf-70000350

Salit IE, Khairnar K, Gough K, Pillai DR. A possible cluster of sexually transmitted Entamoeba histolytica: genetic analysis of a highly virulent strain. Clin Infect Dis [Internet]. 2009 [citado el 15 de mayo de 2023];49(3):346-53. Disponible en: https://doi.org/10.1086/600298

Leder K, Weller P. Extraintestinal Entamoeba histolytica amebiasis. UpToDate [Internet]. 2022 [citado el 14 de mayo de 2023]. Disponible en: https://www.uptodate.com/contents/extraintestinal- entamoeba-histolytica- amebiasis?search=liver%20abscess&source=search_ result&selectedTitle=3~142&usage_type=default&disp lay_rank=3

Valdevenito VM. Manual de Parasitología humana [Internet]. Concepción: UdeC; 2012 [citado el 15 de

mayo de 2023]. Disponible en: http://repositorio.udec.cl/jspui/bitstream/11594/880/2/ Manual_Parasitologia.Image.Marked.pdf

Instituto de Salud Pública de Chile. Vigilancia de diarreas por agentes parasitarios en menores de 5 años Chile 2008 – 2012 [Internet]. Santiago: Gobierno de Chile; 2012 [citado el 15 de mayo de 2023]. Disponible en: https://www.ispch.cl/sites/default/files/boletin_diarreas.pdf

Haque R, Huston CD, Hughes M, Houpt E, Petri WA Jr. Amebiasis. N Engl J Med [Internet]. 2003 [citado el 15 de mayo de 2023];348(16):1565-73. Disponible en: http://dx.doi.org/10.1056/nejmra022710

Salles JM, Salles MJ, Moraes LA, Silva MC. Invasive amebiasis: an update on diagnosis and management. Expert Rev Anti Infect Ther [Internet]. 2007 [citado el 15 de mayo de 2023];5(5):893-901. Disponible en: https://doi.org/10.1586/14787210.5.5.893

Acuna-Soto R, Maguire JH, Wirth DF. Gender Distribution in Asymptomatic and Invasive Amebiasis. Am J Gastroenterol [Internet]. 2000 [citado el 15 de mayo de 2023];95(5):1277-83. Disponible en: https://doi.org/10.1111/j.1572-0241.2000.01525.x

Vidal S, Toloza L, Cancino B. Evolución de la prevalencia de enteroparasitosis en la ciudad de Talca, Región del Maule, Chile. Rev Chilena Infectol [Internet]. 2010 [citado el 15 de mayo de 2023];27(4):336-40. Disponible en: http://dx.doi.org/10.4067/S0716-10182010000500009

InstitutodeSaludPúblicadeChile.Formulariogeneral de envío de muestras clínicas para estudios parasitológicos [Internet]. Santiago: ISPCH; 2023 [citado el 15 de mayo de 2023]. Disponible en: https://www.ispch.cl/wp-content/uploads/2023/02/Anexo-3- IT-213.01-001-FORMULARIO-GENERAL-DE-ENVIO-DE- MUESTRAS-CLINICAS-PARA-ESTUDIOS- PARASITOLOGICOS-v6.pdf

Instituto de Salud Pública de Chile. Amebiasis diagnóstico serológico [Internet]. Santiago: ISPCH; 2022 [citado el 15 de mayo de 2023]. Disponible en: https://www.ispch.cl//wp- content/uploads/prestaciones/571/2330007%20V1%2 016.6.22%20AMEBIASIS%20DIAGNOSTICO%20SE ROLOGICO.pdf

LópezM,QuirozD,PinillaA,Diagnósticodeamebiasis intestinal y extraintestinal. Acta Med Colomb [Internet]. 2008 [citado el 15 de mayo de 2023];33(2):75-83. Disponible en: http://www.scielo.org.co/pdf/amc/v33n2/v33n2a6.pdf

Weitzel T, Cifuentes C. Acceso a antiparasitarios en Chile [Internet]. Concepción: Sociedad Chilena de Infectología; 2018 [citado el 15 de mayo de 2023]. Disponible en: https://www.sochinf.cl/portal/templates/sochinf2008/do cumentos/2019/Acceso_a_Antiparasitarios_en_Chile. pdf

Blessmann J, Khoa ND, Van An L, Tannich E. Ultrasound patterns and frequency of focal liver lesions after successful treatment of amoebic liver abscess: Ultrasound follow-up of amoebic liver abscess. Trop Med Int Health [Internet]. 2006 [citado el 15 de mayo de 2023];11(4):504-8. Disponible en: http://dx.doi.org/10.1111/j.1365-3156.2006.01595.x

FiliceC,DiPerriG,StrosselliM,BrunettiE,DughettiS, Van Thiel DH, et al. Outcome of hepatic amebic abscesses managed with three different therapeutic strategies. Dig Dis Sci [Internet]. 1992 [citado el 15 de mayo de 2023];37(2):240-7. Disponible en: http://dx.doi.org/10.1007/bf01308178

Published

2023-07-31

How to Cite

1.
Oviedo Bravo S, Muñoz Gardilcic N. Amoebic liver abscess: a case report from Santiago, Chile. Rev. Conflu [Internet]. 2023 Jul. 31 [cited 2026 Feb. 3];6(1):132-5. Available from: https://revistas.udd.cl/index.php/confluencia/article/view/923

Issue

Section

Clinical Case

Most read articles by the same author(s)

Similar Articles

1 2 > >> 

You may also start an advanced similarity search for this article.