Percutaneous electrolysis for the treatment of soft tissue injuries: scoping review

Authors

DOI:

https://doi.org/10.52611/confluencia.2025.1183

Keywords:

Electrolysis, Soft tissue injuries, Tendinopathy, Physical therapy modalities, Musculoskeletal pain

Abstract

Introduction: Percutaneous Electrolysis is an invasive physical therapy technique that generates a localized inflammatory process, promoting the repair and regeneration of damaged soft tissue. This technique has been internationally used and applied, often being combined with other physiotherapeutic interventions, thereby reducing associated symptoms and improving functionality in the studied populations. Objective: To map the use and application of percutaneous electrolysis in soft tissue pathologies for pain management and functional improvement as reported in the scientific literature. Methodology: A search strategy was implemented across PubMed, SciELO, Google Scholar, ScienceDirect, and PEDro, yielding a total of 185 articles. Five additional articles were manually identified. The selection process then employed title, abstract, and full-text screening. The variables of interest extracted from each article included “pathology”, “target tissue”, “electrolysis parameters”, “application frequency”, among others. Result: A total of 38 scientific articles were included. This study organizes the outcomes based on changes in pain and functionality in populations treated with Percutaneous Electrolysis. It has been suggested that this technique increases inflammatory markers, aiding pain modulation. This technique has been used in various pathologies such as temporomandibular disorders, rotator cuff tendinopathies, epicondylalgia, and plantar fasciitis, among others. Conclusion: Percutaneous Electrolysis emerges as a promising intervention, particularly for tendinopathies and painful syndromes. Percutaneous Electrolysis demonstrates significant effects in both pain reduction and functional improvement.

Downloads

Download data is not yet available.

References

Abat F, Gelber PE, Monllau J, Sánchez-Ibáñez JM. Large Tear of the Pectoralis Major Muscle in an Athlete. Results after Treatment with Intratissue Percutaneous Electrolysis (EPI®). J Sports Med Doping Stud [Internet]. 2014 [citado el 16 de agosto 2024];4(2):1000139. Disponible en: http://dx.doi.org/10.4172/2161-0673.1000139

Valera-Garrido F, Jiménez-Rubio S, Minaya-Muñoz F, Estévez-Rodríguez JL, Navandar A. Ultrasound-Guided Percutaneous Needle Electrolysis and Rehab and Reconditioning Program for Rectus Femoris Muscle Injuries: A Cohort Study with Professional Soccer Players and a 20-Week Follow-Up. App Sci [Internet]. 2020 [citado el 16 de agosto 2024];10(21):7912. Disponible en: https://doi.org/10.3390/app10217912

Valera-Garrido F, Minaya-Muñoz F. Advanced Techniques in Musculoskeletal Medicine & Physiotherapy [Internet]. España; Elsevier: 2016 [citado el 16 de agosto 2024]. Disponible en: https://evolve.elsevier.com/cs/product/9780702065163?role=student

Arias-Buriá JL, Truyols-Domínguez S, Valero-Alcaide R, Salom-Moreno J, Atín-Arratibel MA, Fernández-de-las-Penãs C. Ultrasound-Guided Percutaneous Electrolysis and Eccentric Exercises for Subacromial Pain Syndrome: A Randomized Clinical Trial. Evid Based Complement Alternat Med [Internet]. 2015 [citado el 16 de agosto 2024]. Disponible en: https://doi.org/10.1155/2015/315219

García-Vidal JA, Salinas J, Escolar-Reina P, Cuello F, Ortega N, de Dios Berná-Mestre J, et al. Galvanic current dosage and bacterial concentration are determinants of the bactericidal effect of percutaneous needle electrolysis: an in vitro study. Sci Rep [Internet]. 2021 [citado el 16 de agosto 2024];11(1). Disponible en: https://doi.org/10.1038/s41598-021-98451-5

Abat F, Diesel WJ, Gelber PE, Polidori F, Monllau JC, Sanchez-Ibañez JM. Effectiveness of the Intratissue Percutaneous Electrolysis (EPI®) technique and isoinertial eccentric exercise in the treatment of patellar tendinopathy at two years follow-up. Muscles Ligaments Tendons J [Internet]. 2014 [citado el 16 de agosto 2024];4(2):188-93. Disponible en: https://pubmed.ncbi.nlm.nih.gov/25332934/

Arias-Buría JL, Truyols-Domínguez S, Valero-Alcaide R, Salom-Moreno J, Atín-Arratibel MA, Fernández-de-Las-Peñas C. Ultrasound-Guided Percutaneous Electrolysis and Eccentric Exercises for Subacromial Pain Syndrome: A Randomized Clinical Trial. Evid Based Complement Alternat Med [Internet] 2015 [citado el 16 de agosto 2024]:315219. Disponible en: https://doi.org/10.1155/2015/315219

Abat F, Valles SL, Gelber PE, Polidori F, Stitik TP, García-Herreros S, et al. Mecanismos moleculares de reparación mediante la técnica Electrólisis Percutánea Intratisular en la tendinosis rotuliana. Rev Esp Cir Ortop Traumatol [Internet]. 2014 [citado el 16 de agosto 2024];58(4):201-5. Disponible en: http://dx.doi.org/10.1016/j.recot.2014.01.002

Sánchez-lbáñez JM, Fernández ME, Monllau JC, Alonso-Díez A, Sánchez-García J, Sánchez-Sánchez JL. New Treatments for Degenerative Tendinopathy, focused on the Region-Specific of the Tendon. Rheumatology [Internet]. 2015 [citado el 16 de agosto 2024];5(4):1000173. Disponible en: http://dx.doi.org/10.4172/2161-1149.1000173

Martínez-Silván D, Santomé-Martínez F, Champón-Chekroun AM, Velázquez-Saornil J, Gómez-Merino S, Cos-Morera MA, et al. Clinical use of percutaneous needle electrolysis in musculoskeletal injuries: A critical and systematic review of the literature. Apunts Sports Med [Internet]. 2022 [citado el 16 de agosto 2024];57(216):100396. Disponible en: https://doi.org/10.1016/j.apunsm.2022.100396

Borrella-Andrés S, Malo-Urriés M, Pérez-Bellmunt A, Arias-Buría JL, Rodríguez-Sanz J, Albarova-Corral MI, et al. Application of Percutaneous Needle Electrolysis Does Not Elicit Temperature Changes: An In Vitro Cadaveric Study. Int J Environ Res Public Health [Internet]. 2022 [citado el 16 de agosto 2024];19(23):15738. Disponible en: https://doi.org/10.3390/ijerph192315738

Berná-Serna J de D, García-Vidal JA, Escolar-Reina MP, Medina-Mirapeix F, Guzmán-Aroca F, Piñero-Madrona A, et al. A New Treatment for Mammillary Fistulas Using Ultrasound-Guided Percutaneous Needle Electrolysis. J Clin Med [Internet]. 2020 [citado el 16 de agosto 2024];9(3). Disponible en: https://doi.org/10.3390/jcm9030649

Peñin-Franch A, García-Vidal JA, Martínez CM, Escolar-Reina P, Martínez-Ojeda RM, Gómez AI, et al. Galvanic current activates the NLRP3 inflammasome to promote Type I collagen production in tendon. eLlife [Internet]. 2022 [citado el 16 de agosto 2024];1(11):e73675. Disponible en: https://doi.org/10.7554/eLife.73675

Margalef R, Minaya-Muñoz F, Valera-Garrido F, Bosque M, Santafé MM. Changes in pH as a result of galvanic currents used in percutaneous needle electrolysis. J Invasive Tech Phys Ther [Internet]. 2020 [citado el 16 de agosto 2024];3(1):6. Disponible en: https://doi.org/10.1055/s-0040-1712511

Belón-Pérez P, Calderón-Díez L, Sánchez-Sánchez JL, Robles-García M, Plaza-Manzano G, Fernández-de-las-Peñas C. Cadaveric and Ultrasound Validation of Percutaneous Electrolysis Approaches at the Arcade of Frohse: A Potential Treatment for Radial Tunnel Syndrome. Int J Environ Res Public Health [Internet]. 2022 [citado el 16 de agosto 2024];19(4):2476. Disponible en: https://doi.org/10.3390/ijerph19042476

Mattiussi G, Moreno C. Treatment of proximal hamstring tendinopathy-related sciatic nerve entrapment: presentation of an ultrasound-guided "Intratissue Percutaneous Electrolysis" application. Muscles Ligaments Tendons J [Internet]. 2016 [citado el 16 de agosto 2024];6(2):248-52. Disponible en: https://doi.org/10.11138/mltj/2016.6.2.248

Varela-Rodríguez S, Sánchez-Sánchez JL, Velasco E, Delicado-Miralles M, Sánchez-González JL. Endogenous Pain Modulation in Response to a Single Session of Percutaneous Electrolysis in Healthy Population: A Double-Blinded Randomized Clinical Trial. J Clin Med [Internet]. 2022 [citado el 16 de agosto 2024];11(10):2889. Disponible en: https://doi.org/10.3390/jcm11102889

de la Cruz Torres B, Albornoz Cabello M, García Bermejo P, Naranjo Orellana J. Autonomic responses to ultrasound-guided percutaneous needle electrolysis of the patellar tendon in healthy male footballers. Acupunct Med [Internet]. 2022 [citado el 16 de agosto 2024];34(4):275-9. Disponible en: https://doi.org/10.1136/acupmed-2015-010993

Bermejo PG, De La Cruz-Torres B, Naranjo-Orellana J, Albornoz-Cabello M. Autonomic Responses to Ultrasound-Guided Percutaneous Needle Electrolysis: Effect of Needle Puncture or Electrical Current? J Altern Complement Med [Internet]. 2018 [citado el 16 de agosto de 2024];24(1):69-75. Disponible en: https://doi.org/10.1089/acm.2016.0339

Lopez-Martos R, Gonzalez-Perez LM, Ruiz-Canela-Mendez P, Urresti-Lopez FJ, Gutierrez-Perez JL, Infante-Cossio P. Randomized, double-blind study comparing percutaneous electrolysis and dry needling for the management of temporomandibular myofascial pain. Med Oral Patol Oral Cir Bucal [Internet]. 2018 [citado el 16 de agosto 2024];23(4):e454-62. Disponible en: https://doi.org/10.4317/medoral.22488

Gonzalez-Perez LM, Vera-Martin R, Montes-Latorre E, Torres-Carranza E, Infante-Cossio P. Botulinum Toxin and Percutaneous Needle Electrolysis for the Treatment of Chronic Masticatory Myalgia. Toxins [Internet]. 2023 [citado el 16 de agosto 2024];15(4):278. Disponible en: https://doi.org/10.3390/toxins15040278

García-Naranjo J, Barroso-Rosa S, Loro-Ferrer JF, Limiñana-Cañal JM, Suarez-Hernández E. A novel approach in the treatment of acute whiplash syndrome: Ultrasound-guided needle percutaneous electrolysis. A randomized controlled trial. Orthop Traumatol Surg Res [Internet]. 2017 [citado el 16 de agosto 2024];103(8):1229-34. Disponible en: https://doi.org/10.1016/j.otsr.2017.09.012

Arias-Buriá JL, Truyols-Domínguez S, Valero-Alcaide R, Salom-Moreno J, Atín-Arratibel MA, Fernández-De-Las-Penãs C. Ultrasound-Guided Percutaneous Electrolysis and Eccentric Exercises for Subacromial Pain Syndrome: A Randomized Clinical Trial. Evid Based Complement Alternat Med [Internet]. 2015 [citado el 16 de agosto 2024]:315219. Disponible en: https://doi.org/10.1155/2015/315219

de Miguel-Valtierra L, Salom-Moreno J, Fernández-de-las-Peñas C, Cleland JA, Arias-Buría JL. Ultrasound-Guided Application of Percutaneous Electrolysis as an Adjunct to Exercise and Manual Therapy for Subacromial Pain Syndrome: A Randomized Clinical Trial. J Pain [Internet]. 2018 [citado el 16 de agosto 2024];19(10):1201-10. Disponible en: https://doi.org/10.1016/j.jpain.2018.04.017

Rodríguez-Huguet M, Góngora-Rodríguez J, Lomas-Vega R, Martín-Valero R, Díaz-Fernández Á, Obrero-Gaitán E, et al. Percutaneous Electrolysis in the Treatment of Lateral Epicondylalgia: A Single-Blind Randomized Controlled Trial. J Clin Med [Internet]. 2020 [citado el 16 de agosto 2024];9(7):1-11. Disponible en: https://doi.org/10.3390/jcm9072068

Valera-Garrido F, Minaya-Muñoz F, Medina-Mirapeix F. Ultrasound-Guided Percutaneous Needle Electrolysis in Chronic Lateral Epicondylitis: Short-Term and Long-Term Results. Acupunct Med [Internet]. 2014 [citado el 16 de agosto 2024];32(6):446-54. Disponible en: https://doi.org/10.1136/acupmed-2014-010619

Benito-de-Pedro AI, Becerro-de-Bengoa-Vallejo R, Losa-Iglesias ME, Rodríguez-Sanz D, Calvo-Lobo C, Benito-de-Pedro M. Efficacy of Deep Dry Needling versus Percutaneous Electrolysis in Ultrasound-Guided Treatment of Active Myofascial Trigger Points of the Levator Scapulae in Short-Term: A Randomized Controlled Trial. Life [Internet]. 2023 [citado el 16 de agosto 2024];13(4):939. Disponible en: https://doi.org/10.3390/life13040939

Rodríguez-Huguet M, Góngora-Rodríguez J, Rodríguez-Huguet P, Ibañez-Vera AJ, Rodríguez-Almagro D, Martín-Valero R, et al. Effectiveness of Percutaneous Electrolysis in Supraspinatus Tendinopathy: A Single-Blinded Randomized Controlled Trial. J Clin Med [Internet]. 2020 [citado el 16 de agosto 2024];9(6):1-13. Disponible en: https://doi.org/10.3390/jcm9061837

R-Moreno MD. Results of the Electrolysis Percutaneous Intratissue in the shoulder pain: infraspinatus, A Randomized Controlled Trial. Rev Cubana Ortop Traumatol [Internet]. 2015 [citado el 16 de agosto 2024];29(1):76-87. Disponible en: http://scielo.sld.cu/pdf/ort/v30n1/ort07116.pdf

López-Royo MP, Ríos-Díaz J, Galán-Díaz RM, Herrero P, Gómez-Trullén EM. A Comparative Study of Treatment Interventions for Patellar Tendinopathy: A Randomized Controlled Trial. Arch Phys Med Rehabil [Internet]. 2021 [citado el 16 de agosto 2024];102(5):967-75. Disponible en: https://doi.org/10.1016/j.apmr.2021.01.073

Muñoz-Fernández AC, Barragán-Carballar C, Villafañe JH, Martín-Pérez S, Alonso-Pérez JL, Díaz-Meco R, et al. A new ultrasound-guided percutaneous electrolysis and exercise treatment in patellar tendinopathy: three case reports. Front. Biosci [Internet]. 2021 [citado el 16 de agosto 2024];26(11):1166-75. Disponible en: https://doi.org/10.52586/5017

Iborra-Marcos Á, Ramos-Álvarez JJ, Rodríguez-Fabián G, Del Castillo-González F, López-Román A, Polo-Portes C, et al. Intratissue Percutaneous Electrolysis vs Corticosteroid Infiltration for the Treatment of Plantar Fasciosis. Foot Ankle Int [Internet]. 2018 [citado el 16 de agosto 2024];39(6):704-11. Disponible en: https://doi.org/10.1177/1071100718754421

Abat F, Gelber PE, Polidori F, Monllau JC, Sanchez-Ibañez JM. Clinical results after ultrasound-guided intratissue percutaneous electrolysis (EPI®) and eccentric exercise in the treatment of patellar tendinopathy. Knee Surg Sports Traumatol Arthrosc [Internet]. 2015 [citado el 16 de agosto 2024];23(4):1046-52. Disponible en: https://doi.org/10.1007/s00167-014-2855-2

Valera-Garrido V, Minaya-Muñoz F, Sánchez-Ibáñez JM. Efectividad de la electrólisis percutánea intratisular (EPI®) en las tendinopatías crónicas del tendón rotuliano. Trauma Fund MAPFRE [Internet]. 2010 [citado el 16 de agosto 2024];21(4):227-36. Disponible en: https://www.mvclinic.es/wp-content/uploads/2010_Valera_Efectividad-de-la-electr%C3%B3lisis-percut%C3%A1nea-intratisular-EPI-en-las-tendinopat%C3%ADas-cr%C3%B3nicas-del-tend%C3%B3n-rotuliano.pdf

Abat F, Diesel WJ, Gelber PE, Polidori F, Monllau JC, Sanchez-Ibañez JM. Effectiveness of the Intratissue Percutaneous Electrolysis (EPI®) technique and isoinertial eccentric exercise in the treatment of patellar tendinopathy at two years follow-up. Muscles Ligaments Tendons J [Internet]. 2014 [citado el 16 de agosto 2024];4(2):188-93. Disponible en: https://pmc.ncbi.nlm.nih.gov/articles/PMC4187605/

Arias-Buriá JL, Truyols-Domínguez S, Valero-Alcaide R, Salom-Moreno J, Atín-Arratibel MA, Fernández-de-las-Penãs C. Ultrasound-Guided Percutaneous Electrolysis and Eccentric Exercises for Subacromial Pain Syndrome: A Randomized Clinical Trial. Evid Based Complement Alternat Med [Internet]. 2015 [citado el 16 de agosto 2024];1:315219. Disponible en: https://doi.org/10.1155/2015/315219

Moreno C, Mattiussi G, Núñez FJ, Messina G, Rejc E. Intratissue percutaneous electolysis combined with active physical therapy for the treatment of adductor longus enthesopathy-related groin pain: a randomized trial. J Sports Med Phys Fitness [Internet]. 2017 [citado el 16 de agosto 2024];57:1318-29. Disponible en: https://doi.org/10.23736/S0022-4707.16.06466-5

Viatris. VIATRIS™ offers savings programs for EPIPEN® Auto-Injector and its authorized generic [Internet]. Pennsylvania; Viatris: 2017 [citado el 16 de agosto 2024]. Disponible en: https://www.epipen.com/en

Valera-Calero JA, Sánchez-Mayoral-Martín A, Varol U. Short-term effectiveness of high- and low-intensity percutaneous electrolysis in patients with patellofemoral pain syndrome: A pilot study. World J Orthop [Internet]. 2021 [citado el 16 de agosto 2024];12(10):781-90. Disponible en: https://doi.org/10.5312/wjo.v12.i10.781

Sánchez-Lorenzo M, Seoane-Pardo R. Ultrasound-guided percutaneous needle electrolysis and therapeutic exercise in Achilles tendinopathy: A case study. Fisioterapia [Internet]. 2018 [citado el 16 de agosto 2024];40(6):331-5. Disponible en: https://doi.org/10.1016/j.ft.2018.07.005

Al-Boloushi Z, Gómez-Trullén EM, Arian M, Fernández D, Herrero P, Bellosta-López P. Comparing two dry needling interventions for plantar heel pain: a randomised controlled trial. BMJ Open [Internet]. 2020 [citado el 16 de agosto 2024];10(8):e038033. Disponible en: https://doi.org/10.1136/bmjopen-2020-038033

Fernández-Rodríguez T, Fernández-Rolle Á, Truyols-Domínguez S, Benítez-Martínez JC, Casaña-Granell J. Prospective Randomized Trial of Electrolysis for Chronic Plantar Heel Pain. Foot Ankle Int [Internet]. 2018 [citado el 16 de agosto 2024];39(9):1039-46. Disponible en: https://doi.org/10.1177/1071100718773998

Margalef R, Valera-Garrido F, Minaya-Muñoz F, Bosque M, Ortiz N, Santafe MM. Percutaneous Needle Electrolysis Reverses Neurographic Signs of Nerve Entrapment by Induced Fibrosis in Mice. Evid Based Complement Alternat Med [Internet]. 2020 [citado el 16 de agosto 2024];1:6615563. Disponible en: https://doi.org/10.1155/2020/6615563

Published

2025-07-15

How to Cite

1.
Dellafiori Lillo JT. Percutaneous electrolysis for the treatment of soft tissue injuries: scoping review. Rev. Conflu [Internet]. 2025 Jul. 15 [cited 2025 Jul. 17];8. Available from: https://revistas.udd.cl/index.php/confluencia/article/view/1183

Issue

Section

Revisión Bibliográfica

Similar Articles

1 2 3 > >> 

You may also start an advanced similarity search for this article.